Baytown is a city within Harris County and partially in Chambers County in the Gulf Coast region of the U.S. state of Texas. Located within the Houston–The Woodlands–Sugar Land metropolitan area, it lies on the northern side of the Galveston Bay complex near the outlets of the San Jacinto River and Buffalo Bayou. It is the sixth-largest city within this metropolitan area. Major highways serving the city include State Highway 146 and Interstate 10. As of 2010, Baytown had a population of 71,802, and it had an estimated population of 75,992 in 2016.